The fresh good black line presents the fresh new U-shaped relationships between your carried on x and you may record relative chances
Schematic diagram of the optimal equal-HR method. The red dashed line is parallel to the x-axis, which means Pstep one and Pdos have equal log relative hazard values. The optimal equal-HR method searches pairs of cut-points with equal log relative hazard values as candidate cut-points, such as (P1, P2)
The remainder of so it report was organized below. The facts of your optimal equal-Hour method was showed from inside the 2nd Part ‘Tips’. Brand new performance of your maximum equal-Hours experience compared with other widely used discretization steps out-of discrimination stamina and you will results via a simulation study. I expose the brand new simulator settings inside the Area ‘The new Simulator Study’. The outcome of simulator analysis as well as the application of the latest optimum equivalent-Hr approach on the a bona fide dataset from small cellphone cancer of the lung is showed for the Part ‘Results’. Fundamentally, you can find talk and you will findings.
where h(t) denotes the hazard function, h0(t) denotes the baseline hazard function, t is the observed survival times, X is a vector of covariates, and ? is a vector of estimated regression coefficients. The relative hazard ? can be calculated as the above equation divided by h0(t) in both side:
The perfect equal-Hours means uses record(?) values to find optimal slashed-things. Risk rates (HR) is with ease computed throughout the relative danger ? Read More